Both TVs come with smart platforms that support popular streaming apps and voice control features. Both TVs offer adequate brightness levels suitable for most indoor lighting conditions. Both TVs provide decent motion handling, making them suitable for everyday viewing including sports and action content. Both TVs provide standard built-in audio performance suitable for regular usage, though external speakers can enhance the experience. Both TVs come in similar screen sizes, making them suitable for comparable viewing setups and room environments. Panasonic TH-65MX660DX and Samsung UA65U8100FULXL differ in resolution (4K vs 4K 3840 x 2160), which can affect overall clarity and sharpness of the display. Panasonic TH-65MX660DX and Samsung UA65U8100FULXL are two competitive smart TVs offering a mix of display performance, smart features, and overall value for different types of users. In general, both TVs cater to modern entertainment needs, including streaming, gaming, and everyday viewing.

Verdict: Both TVs are strong contenders, and your final choice should depend on your preference for screen size, motion performance, and smart features.